KMID : 0361420120360010159
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Journal of Korean Academy of Rehabilitation Medicine 2012 Volume.36 No. 1 p.159 ~ p.162
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Cefepime Neurotoxicity in Patients with Renal Insuffi ciency
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Kim Seon-Yu
Lee In-Sik Park Seung-Lee Lee Jong-Min
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Abstract
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Cefepime is a fourth-generation cephalosporin that is active against both gram-positive and gram-negative organisms. It is administered parenterally for the treatment of severe infections. Approximately 85% of the drug is excreted unchanged by the kidneys. Neurotoxicity in patients with renal failure who are treated with cefepime has been reported sporadically. We report on two senile patients with renal impairment who developed neurotoxicity including lethal outcome after treatment with cefepime.
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KEYWORD
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Cefepime, Neurotoxicity, Renal failure
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